Bioimaging

BIOIMAGING

Director: Xinmai Yang, Ph.D.

Bioimaging science is an evolving field of biomedicine and bioengineering that involves the development and application of imaging technologies and computational software tools to answer biological questions in life sciences. This discipline brings together engineers, computer scientists, physicists, biologists, chemists and clinicians engaged in the development of equipment and methodologies for characterizing tissue properties and examining its structure and function through in vivo or ex vivo visualization at multiple resolutions, ranging from molecular and cellular to organ level. The imaging technologies are mainly based on the principles of optics, photonics, magnetic resonance, nuclear medicine, radiation, ultrasonics and spectroscopy. Modern applications of bioimaging include multi-photon imaging, image-guided interventional procedures, surgical planning, oncology treatment planning, endoscopic and laparoscopic surgeries and virtual telemedicine. Image processing and analysis is an important part of bioimaging and allows measurement and quantification of anatomical, physiological and/or clinically meaningful parameters. This track is closely linked to the other tracks of the bioengineering program because of supplying critical supportive data. For example, as part of bioimaging, gene-array imaging and analysis provide data for mining with the techniques used in bioinformatics.

As the students in this track are prepared for careers in industry, academia and public service, they are trained in the current bioimaging modalities; fundamentals of physical and mathematical principles and operations, hardware and software, image contrast produced and its interpretation, image quality analysis and measures, quality control tests with phantoms, receiver operating characteristics and target detectability, molecular and cellular contrast agents. Students are exposed to in vivo and ex vivo applications and learn biomarkers specific to individual modality and their utilities. Students use this knowledge to interpret the image contrast for understanding the basic anatomical and physiological relationships in normal and abnormal (e.g. disease) states and for accurate and reproducible clinical diagnosis or visualization.

 

 

Track Faculty

Headshot of Cory Berkland
  • Professor, Chemical and Petroleum Engineering
  • Professor, Pharmaceutical Chemistry
785-864-1455
320E Multidisciplinary Research Building

Associated Tracks

Bioimaging
Biomaterials & Tissue Engineering
Biomedical Product Design & Development
Biomolecular Engineering

Research Interests

Nanoparticles and Colloids in Pharmaceuticals and Biomedicine

Headshot of William Brooks
913-588-9075
Hoglund Brain Imaging Center, KUMC

Titles

Director, Hoglund Brain Imaging Center
Professor, Neurology

Associated Tracks

Bioimaging

Research Interests

Imaging Studies in Cognitive Recovery from Brain Injury and Stroke

Headshot of Jeffrey Burns
913-588-0073
Alzheimer's Disease Center, KUMC

Titles

Professor, Neurology
Associate Director, Alzheimer's Disease Center

Associated Tracks

Bioimaging

Research Interests

Utilizing MRI to examine how lifestyle factors such as exercise and diet influence brain aging and Alzheimer's

Headshot of In-Young Choi
913-588-0174
Hoglund Brain Imaging Center, KUMC

Titles

Professor, Neurology

Associated Tracks

Bioimaging

Research Interests

Developing neuroimaging (magnetic resonance spectroscopy and imaging) and signal processing methods to study brain bioenergetics and metabolic changes with aging and neurodegeneration in clinical and preclinical studies.  

Headshot of András Czirók
913-945-6683
2005 Wahl Hall East, KUMC

Titles

Associate Professor, Anatomy and Cell Biology

Associated Tracks

Bioimaging

Research Interests

Vasculogenesis
Tissue Movements During Early Development
Extracellular Matrix Assembly
Multicellular Motility

  • Director, Bioengineering
  • Professor, Mechanical Engineering
785-864-2994
1132D Learned Hall

Associated Tracks

Bioimaging
Biomaterials & Tissue Engineering
Biomechanics & Neural Engineering
Biomedical Product Design & Development

Research Interests

Tissue Mechanics
Computational Joint Mechanics

Headshot of Kathleen Gustafson
913-588-0065
Hoglund Brain Imaging Center, KUMC

Titles

Research Assistant Professor, Neurology

Associated Tracks

Bioimaging

Research Interests

Use of sophisticated signal processing of electrophysiologic cardiac signals to understand fetal autonomic nervous system development (fetal imprinting) and infant visual development

Headshot of Ron Hui
785-864-8814
3026 Eaton Hall

Titles

Professor, Electrical Engineering & Computer Science

Associated Tracks

Bioimaging
Biomedical Product Design & Development

Research Interests

Optical/RF Measurement and Bioscensors
Novel Photonic Devices
Optical Communication Systems

Headshot of Phil Lee
913-588-0454
G035 Hoglund Brain Imaging Center, KUMC

Titles

Associate Professor, Molecular and Integrative Physiology

Associated Tracks

Bioimaging

Research Interests

In vivo characterization of neurodegenerative diseases using novel MRI techniques

Headshot of Charles Little
913-588-1856
G015 Wahl Hall East, KUMC

Titles

Professor, Anatomy and Cell Biology

Associated Tracks

Bioimaging

Research Interests

Computational analysis of cell and tissue dynamics during early embryogenesis, the Cell Biology of Vascular Pattern Formation, Physical Mechanisms of Morphogenesis, Cell Surface-Extracellular Matrix Interactions, Developmental Malformations

Headshot of Anil Misra
785-864-1750
5102C Learned Hall

Titles

Professor, Civil, Environmental and Architectural Engineering

Associated Tracks

Bioimaging
Biomaterials & Tissue Engineering
Biomechanics & Neural Engineering
Biomedical Product Design & Development

Research Interests

Nano-micro-macro mechanics of calcified and soft tissues, constitutive modeling and computational methods, scanning acoustic microscopy and ultrasonic testing

Headshot of Jules Nazzaro

Titles

Director, Stereotactic and Functional Neurosurgery Program
Vice Chair Education, Neurosurgery
Associate Professor, Neurosurgery

Associated Tracks

Bioimaging

Research Interests

Deep Brain Stimulation (DBS)

Randy Nudo, Ph.D.
913-588-1247
220K Landon Center on Aging, KUMC

Titles

Professor & Vice Chair of Research, Department of Rehabilitation Medicine
Director, Landon Center on Aging

Associated Tracks

Bioimaging
Biomechanics & Neural Engineering
Biomedical Product Design & Development

Research Interests

Neural Mechanisms of Recovery after Brain Injury
implantable Devices for Brain Plasticity

Headshot of Brenda Rongish
913-588-1878
1012 Wahl Hall West, KUMC

Titles

Associate Professor, Anatomy and Cell Biology

Associated Tracks

Bioimaging

Research Interests

"Research in the lab is interdisciplinary and focuses on the dynamic nature of the extracellular matrix, the milieu that surrounds the cells, and contributes to their shape, locomotion, gene expression, and every aspect of their behavior...To study these dynamic molecules we use automated microscopes and fluorescent probes to perform time-lapse imaging of avian developmental events and the role of the ECM in these events."

Eduardo Rosa-Molinar
785-864-3091
Haworth Hall 3015

Titles

Professor, Pharmacology and Toxicology and Neuroscience Graduate Program/Director, Microscopy and Analytical Imaging Resource Core Lab

Associated Tracks

BioImaging

Research Interests

The development and application of tools and workflows for multi-scale multi-modal correlated volume microscopies and three-dimensional volume reconstruction to unravel synaptic geometry

913-588-5129
1017 Breidenthal

Titles

Assistant Professor, Director of Basic Research

Associated Tracks

Biomechanics & Neural Engineering
Computational Bioengineering
Bioimaging

Research Interests

Neural encoding of hand and finger movements
Brain-machine interfaces
Data science/machine learning for neurotechnologies

Neil Segal
913-945-8985
Sudler 1038

Titles

Professor, Director of Clinical Research

Associated Tracks

Bioimaging; Computational Bioengineering

Research Interests

Rehabilitation Medicine

Headshot of Suzanne Shontz
  • Track Director, Computational Bioengineering
  • Associate Professor, Electrical Eng. and Computer Sci.
785-864-8816
2001 Eaton Hall

Associated Tracks

Bioimaging
Computational Bioengineering
Biomechanics & Neural Engineering
Biomedical Product Design & Development

Research Interests

Computational Medicine
Computational Surgery
Computational Anatomy
Computational Biomechanics
Patient-Specific Model and Mesh Generation
Image Processing

Headshot of Teruna Siahaan
785-864-7327
201D Simons Laboratories

Titles

Professor, Pharmaceutical Chemistry

Associated Tracks

Bioimaging
Biomolecular Engineering

Research Interests

Utilizing cell adhesion molecules for targeted drug delivery and tissue engineering

Paulette Spencer, D.D.S., Ph.D.
  • Director, Institute for Bioengineering Research
  • Deane E. Ackers Distinguished Professor, Mech. Eng.
785-864-8140
3111 Learned Hall

Associated Tracks

Bioimaging
Biomaterials & Tissue Engineering
Biomedical Product Design & Development

Research Interests

Professor Spencer and her research team are designing, synthesizing, and developing novel biomaterials for the repair and replacement of mineralized tissues. Under in vivo conditions, failure of a repair or replacement generally begins at the biomaterial/tissue interface and thus, a key aspect of our work is understanding the fundamental phenomena that control biological interactions at material interfaces.

Ilya Vakser
785-864-1057
200A Multidisciplinary Research Building

Titles

Director, Center for Computational Biology
Professor, Molecular Biosciences

Associated Tracks

Bioinformatics

Research Interests

Development of molecular recognition methods for structural genomics and bioinformatics

Danny Welch
913-945-7739
2003 Wahl Hall West, KUMC

Titles

Professor and Chair, Cancer Biology
Associate Director for Basic Sciences
Associate Director for Education

Associated Tracks

Bioimaging
Computational Bioengineering
Biomolecular Engineering

Research Interests

Tumor progression, invasion, metastasis,

Liang Xu
785-864-6319
3185 ISB

Titles

Professor, Molecular Bioscience

Associated Tracks

Biomaterials, Bioimaging

Research Interests

Drug discovery
Drug delivery
Cell biology/engineering
Genetic engineering
Nanotechnology

Xinmai Yang Ph.D.
  • Track Director, Bioimaging
  • Associate Professor, Mechanical Engineering
785-864-1753
5101F Learned Hall

Associated Tracks

Bioimaging

Research Interests

Photoacoustic Imaging
Biomedical Ultrasound